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Lubrizol’s Apisolex Technology is Grand Winner of the 7th Annual Medicine Maker Innovation Awards

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Berkshire Hathaway’s Lubrizol Life Science (LLS) – Health, a pharmaceutical company based in Cleveland, Ohio, has been awarded The Medicine Maker 2022 Innovation Award for its revolutionary technology – Apisolex™ Polymer solubilizing excipient.

The Apisolex solubilizing excipient is designed to enhance the solubility of BCS class II and IV APIs by up to 50,000-fold, allowing medications that would have otherwise been discarded to reach the market. The technology is injectable grade and designed to work with simple formulation techniques, streamlining manufacturing and minimizing API loss. It can be mixed with an aqueous-based solution, followed by sterile filtration and lyophilization to form micellar structures that encapsulate the API during lyophilization. The resulting formulation is stable and can be readily resuspended in common diluents for administration, reconstituting in less than 30 seconds in saline.

Apisolex technology stood out from a record number of nominations received, and readers and visitors to The Medicine Maker website voted for their favorite technology. LLS Health emerged as the grand winner.
Joey Glassco, Senior Global Market Manager, Parenterals at LLS Health, expressed her gratitude for the recognition, saying, “We are honored for Apisolex solubilizing excipient to be recognized by readers of The Medicine Maker for this prestigious innovation award. My hope is that winning this award will allow drug formulators struggling with water-insoluble APIs to discover the polymer’s benefits so that more life-changing medications can make it to market.”

Gaurab Sengupta, Senior Global Business Director, Pharmaceuticals & Nutraceuticals at LLS Health, conveyed what this award means to LLS – Health, saying, “This recognition highlights our commitment to delivering innovative solutions that address critical challenges in the pharmaceutical industry. We’ve zeroed in on a clear unmet need in the solubility enhancement market for critical life-changing drugs. This award demonstrates we are on the right track, validating our efforts to ensure this product is successful.” The Medicine Maker Innovation Awards showcase new drug development and manufacturing technology that has been introduced to the market in 2022. The award signifies LLS Health’s significant contribution to the pharmaceutical industry with its innovative solution. We can expect to learn more about this technology in a future issue of The Medicine Maker.

© 2023 David Mazor

Disclosure: David Mazor is a freelance writer focusing on Berkshire Hathaway. The author is long in Berkshire Hathaway, and this article is not a recommendation on whether to buy or sell a stock. The information contained in this article should not be construed as personalized or individualized investment advice. Past performance is no guarantee of future results.

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